The ascorbic and amino acids (Lp(a) binding inhibitors) recommended by Linus Pauling for coronary heart disease are scientifically proven to:

Lower cholesterol as a natural HMG-CoA reductase inhibitor

Diminish, dissolve and reverse atherosclerotic plaque by
inhibiting the binding of Lp(a) to the arterial wall

Relieve the pain of angina pectoris

Reduce the likelihood of blood clotting, heart attack or
stroke

Strengthen the cardiovascular system by increasing the
formation of collagen

Increase heart and other muscle strength and stamina

Reduce blood and tissue lipids (fats)

Replace the missing "stress" hormone

Increase antioxidant intake and activity to slow aging

Help natural immunity against bacterial, viral, and fungal
diseases, including antibiotic-resistant strains

Promote overall health and the feeling of well-being


Lower cholesterol as a natural HMG-CoA reductase inhibitor. According to Inhibition of human leukocyte 3-hydroxy-3-methylglutaryl coenzyme A reductase activity by ascorbic acid (http://www.jbc.org/cgi/content/abstract/261/16/7127), vitamin C is the original HMG-CoA reductase inhibitor.               TOP

Diminish, dissolve and reverse atherosclerotic plaque by inhibiting the binding of Lp(a) to the arterial wall.  According to the Pauling/Rath Unified Theory, and supported by U.S. Patent #5,230,996, Lp(a) binding inhibitors increase the blood flow as plaque in the arterial wall dissolves.  The patent identifies lysine, lysine analogs e.g. proline, and vitamin C as Lp(a) binding inhibitors. These substances in concentration begin a chemical process that reverses the occlusion, making the artery better able to dilate as needed.  It has long been recognized that ascorbic acid (vitamin C) is in some way related to atherosclerosis. One of the great medical discoveries was of the Lysine Binding Site (LBS) on the walls of blood vessels.  These binding sites are created by lesions (injury) and attract Lp(a) cholesterol, which forms the initial plaque deposits.  Pauling and Rath put these two independent findings together and theorized that a vitamin C deficiency in humans leads to the formation of lesions that cause Lp(a)-based plaque to form. Pauling said, "Knowing that lysyl residues are what causes lipoprotein(a) to get stuck to the wall of the artery and form atherosclerotic plaques, any physical chemist would say at once that the thing to do is prevent that by putting the amino acid lysine in the blood to a greater extent than it is normally. You need lysine to be alive, it is essential: You have to get about 1 gram a day to keep in protein balance, but you can take lysine, pure lysine, a perfectly non toxic substance in food , as pills, which puts extra lysine molecules in the blood. They enter into competition with the lysyl residues on the wall of arteries and accordingly count to prevent Lp(a) from being deposited, or even will work to pull it loose and destroy atherosclerotic plaques." Researchers at the University of Chicago discovered a new Lp(a) binding site, the Proline Binding Site, and report that the amino acid proline may inhibit the binding of Lp(a) up to ten times more effectively than lysine in the test tube.  The Lp(a) in Rhesus monkeys only binds to the proline binding site, so only proline, not lysine, can be predicted to have the anti-plaque effect in these monkeys.  Human Lp(a) has an affinity for both lysine and proline binding sites.   TOP

Relieve the pain of angina pectoris.  Chest pain is the one symptom of heart disease that many people have prior to a heart attack. This pain is a signal that the heart muscle needs more nutrients and oxygen.  That oral vitamin C and lysine can reduce angina pectoris pain is documented by case reports, and this effect has been reported ever since Linus Pauling began recommending high dosage lysine and vitamin C in 1991. For decades doctors have recommended nitroglycerin for angina, not knowing why or how this substance relieves the pain.  Now they do.  Nitroglycerin helps create a short-lived molecule in the body, nitric oxide (NO). NO dilates arteries which improves blood flow, and as a result angina pain is temporarily relieved.  Vitamin C and lysine work differently to relieve the pain by improving blood circulation, not by dilating arteries. Although evidence to date is largely anecdotal, there are now some studies that document this effect.  Reduction in chest pain has been reported so consistently, and the substances involved are so safe, that even the great scientist Pauling said that an expensive study should not be required before people should be advised to take vitamin C and lysine.
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Reduce likelihood of blood clotting, heart attack or stroke. Vitamin E also plays a pivotal role in the inhibition of platelet aggregation. Platelets aggregate because arachidonic acid is converted into pro-aggregatory thromboxanes; this conversion is an oxidative process responsive to vitamin E treatment.  The ability of vitamin E to inhibit platelet aggregation is vitally important, as excessive, uncontrolled platelet aggregation is now acknowledged to be a primary causative factor in myocardial infarction.  An ancillary mechanism involves vitamin E's ability to block redox cycling of catecholamines -the net result being a diminution in abnormal sympathetic stimulation of the heart.  Due to a recent Harvard study by Rimm, et al., orthodox medicine now recognizes the importance of vitamin E as a preventive and treatment for cardiovascular disease.
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Strengthen the cardiovascular system by increasing the formation of collagen.  One important function of vitamin C is the formation and maintenance of collagen, the basis of connective tissue, which is found in skin, ligaments, cartilage, vertebral discs, joint linings, capillary walls, and the bones and teeth.  Collagen, and thus vitamin C, is needed to give support and shape to the body, to help wounds heal, and to maintain healthy blood vessels.  Specifically, ascorbic acid works as a coenzyme to convert proline and lysine to hydroxyproline and hydroxylysine, both important to the collagen structure. The Pauling/Rath Unified Theory holds that it is the lack of collagen, caused by inadequate vitamin C intake, that reduces the structural integrity of human blood vessels. Weakened veins and arteries are susceptible to lesions, especially in stressful areas where blood vessels are stretched.  These lesions result in the formation of atherosclerotic plaques, commonly called heart disease. Tower's formulas Heart Tech® and Ascorsine-9® both contain the three basic collagen building blocks - vitamin c, lysine and proline - required by the body to abundantly create the collagen molecule.           TOP

Increase heart and other muscle strength and stamina.  The human heart is our hardest working muscle.  L-Carnitine, coenzyme Q10, magnesium, and vitamin E all interact in the mitochondrial generation of energy. Carnitine carries fats across the inner membrane for beta-oxidation. Coenzyme Q10 is the key factor in the electron transport system. Magnesium is an essential cofactor for many of the enzyme systems which support energy production. Moreover, it is required for ATP stability, as ATP is synthesized as the magnesium complex. Vitamin E is in the membrane where it can scavenge the free radicals generated by the electron transport system. L-carnitine (the rate determining factor in beta oxidation) increases ATP generation via its effects on beta oxidation, as well as its role in the removal of acetyl units from the mitochondria. The latter process is important because accumulation of acetyl units is known to inhibit various parts of the respiratory process. Other important actions of L-carnitine include vasodilatation of the blood vessels and increased ability to sustain cardiac contractions. Coenzyme Q10 is an integral part of the electron transport system, and hence regulates the ATP-generating capabilities. In addition to its well-known role in carrying electrons, recent studies have shown that coenzyme Q10 transports protons for the proton gradient used to drive oxidative phosphorylation. The latter, of course, is required for ATP synthesis. Thus, coenzyme Q10 plays a pivotal role in all energy generating systems. All organisms with an Electron Transport System have an absolute requirement for coenzyme Q10. Both animal and human studies have unequivocally proven the beneficial effects of supplementary coenzyme Q10 in numerous types of heart disease, as well as hypertension and stroke. (Heart Tech® does not contain any minerals.  Magnesium, a bulk mineral, is not tolerated as well by some people.  For those consumers who have no problems taking magnesium, we offer Ascorsine-9®, which contains the added benefit of magnesium.)   TOP

Reduce blood and tissue lipids (fats).  Ascorbic acid also helps thyroid hormone production, and it aids in cholesterol metabolism, increasing its elimination and thereby assisting in lowering blood cholesterol. Supplemental L-carnitine has been well- documented to reduce blood and tissue lipids, which is associated with a reduced risk of developing heart disease.  Lipids provide 60-80% of the metabolic energy required by the heart, which explains why such high levels of L-carnitine are stored in cardiac muscle.  Moreover, interference with fatty acid oxidation can have dire consequences on myocardial function.  Cognizance of L-carnitine's import has led to numerous investigations, the results of which have documented its cardiovascular benefits in both animals and humans. Carnitine is perhaps best known for its lipid-lowering activity, specifically, its ability to rapidly and markedly decrease plasma triglycerides and increase HDL (good) cholesterol. TOP

Replace the missing "stress" hormone. Vitamin C also aids in the metabolism of tyrosine, folic acid, and tryptophan. Tryptophan is converted in the presence of ascorbic acid to 5-hydroxytryptophan, which forms serotonin, an important brain chemical. Vitamin C also helps folic acid convert to its active form, tetrahydrofolic acid, and tyrosine needs ascorbic acid to form the neurotransmitter substances dopamine and epinephrine. Vitamin C stimulates adrenal function and the release of norepinephrine and epinephrine (adrenaline), our stress hormones; however, prolonged stress depletes vitamin C in the adrenals and decreases the blood levels.   TOP

Increase antioxidant intake and activity. Vitamin C is an antioxidant vitamin. By this function, it helps prevent oxidation of water-soluble molecules that could otherwise create free radicals that generate cellular injury and disease. Vitamin C also indirectly protects the fat-soluble vitamins A and E as well as some of the B vitamins such as riboflavin, thiamine, folic acid, and pantothenic acid from oxidation. Ascorbic acid acts as a detoxifier and may reduce the side effects of drugs such as cortisone, aspirin, and insulin; it may also reduce the toxicity of the heavy metals lead, mercury, and arsenic. Vitamin E is the major lipid-soluble antioxidant.  A substantial body of evidence has accumulated on vitamin E's therapeutic as well as preventive actions against diseases of the heart and blood vessels. Supplemental vitamin E, for example, is known to decrease LDL oxidation, which reduces macrophage-mediated (inflammatory) damage to endothelial cells, thereby preventing the production of foam cells and plaque which are characteristic of atherosclerosis. By blocking inflammation, vitamin E acts as a primary defense against cardiovascular diseases.      TOP

Help natural immunity against bacterial, viral, and fungal diseases, including antibiotic-resistant strains. Vitamin C is being shown through continued research to stimulate the immune system; through this function, along with its antioxidant function, it may help in the prevention and treatment of infections and other diseases. Ascorbic acid may activate neutrophils, the most prevalent white blood cells that work on the front-line defense in more hand-to-hand combat than other white blood cells. It also seems to increase production of lymphocytes, the white cells important in antibody production and in coordinating the cellular immune functions. In this way also, C may be helpful against bacterial, viral, and fungal diseases. In higher amounts, ascorbic acid may actually increase interferon production and thus activate the immune response to viruses; it may also decrease the production of histamine, thereby reducing immediate allergy potential. M. Levine's team at the National Institutes of Health, as reported in SCIENCE, have suggested that their research indicates vitamin C is a potential weapon against antibiotic resistant bacteria. TOP

Promote overall health and the feeling of well-being. According to Cheraskin, et al., in The Ideal Daily Lysine Intake (1977)  the greater the lysine intake, the healthier the subjects in their study.  In 1992 Enstrom proved that 500 mg of vitamin C daily can extend life by more than 5 years. Pauling estimated that the nutrients in Heart Tech® and Ascorsine-9® in amounts much larger than the Recommended Daily Allowances (RDAs) can extend the period of really good health and well-being by 15 - 20 years.                    TOP

The individual components of the Heart Tech® and Ascorsine-9® cocktails have been shown to be therapeutically effective; more importantly, they are practical, and hence patient compliance is not a problem. Heart Tech® and Ascorsine-9® are completely safe, and no toxic side-effects have ever been reported (except the laxative effect of ascorbic acid). In addition to being effective and safe, Heart Tech® and Ascorsine-9® are quite inexpensive when compared with currently prescribed pharmaceutical drugs.  Their cost is even more impressive when compared to the mechanical procedures (e.g., heart transplantation and bypass surgery) that are major contributors to the spiraling cost of healthcare.  Tower's Pauling therapy formulas are effective, easy, and economical; what more could one possibly expect in clinical medicine? TOP
Vitamin C as
  L-ascorbic acid
L-lysine
L-proline
Vitamin A
Vitamin E
Vitamin B2
L-arginine
Vitamin B6
Folic acid
Stevia
HeartTech® Formula
30 servings per jar
3,000 mg

3,000 mg
400 mg
5,000 IU
422 IU
3 mg
200 mg
25 mg
400 mcg

Vitamin C as
L-ascorbic acid
L-lysine
Chondroitin
  sulfate CS/C
Taurine
L-proline
Vitamin A
Vitamin E
L-arginine
Vitamin B6
Magnesium
Creatine
Vitamin B2
Folic acid
Stevia
Ascorsine-9® Formula
3,000 mg

3,000 mg
1,000 mg

1,000 mg
500 mg
8,500 IU
422 IU
200 mg
50 mg
150 mg
844 mg
2 mg
400 mcg

30 servings per jar

TECHNICAL BENEFITS
OF THE VITAMINS AND AMINOS
IN PAULING'S THERAPY

Vitamin C as
  L-ascorbic acid
L-lysine
Stevia
CardioAde® Formula
30 servings per jar
5,000 mg

5,000 mg

Products
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